Buspar
Buspar
Buspar (Buspirone)Application
Generalized disturbing disorder, panic disorder, a syndrome of a vegetative dystonia, a syndrome of an alcoholic abstinence (auxiliary therapy), depression (auxiliary therapy).
Contraindications
Hypersensitivity, serious disturbances of function of kidneys and a liver, a glaucoma, a myasthenia gravis, pregnancy, feeding by a breast.
Restrictions to application
Age till 18 years (safety and efficiency of application are not defined).
Application at pregnancy and feeding by a breast: It is contraindicative at pregnancy. For the period of treatment it is necessary to stop thoracal feeding.
Side effects
From nervous system and sense organs: giddiness (12 %), drowsiness (10 %), a headache (6 %), nervousness (5 %), weariness (4 %), dream disturbance (3 %), dropping of ability to concentration of attention (2 %); extrapyramidal disorders (very seldom); 2 % - a sight illegibility, confusion of consciousness or depression, delicacy, a numbness; 1 % - neurologic symptoms (delicacy of muscles, a pricking, a pain or delicacy in arms or feet, uncontrollable movements of a trunk).
From cardiovascular system and blood (a hemopoiesis, a hemostasis): 1 % - a tachycardia / strong palpitation.
From organs GASTROINTESTINAL TRACT: a nausea (8 %), dryness in a mouth (3 %), a diarrhoeia (2 %); 1 % - vomiting, a constipation; appetite dropping.
The other: spastic strictures, cramps or a muscle tension, an eruption, a sweating.
Interaction
At a combination to inhibitors MAO probably development of a hypertensive crisis.
Overdosage
Symptoms: a nausea, vomiting, etc. , giddiness, a miosis, drowsiness.
Treatment: a gastric lavage, appointment of the activated coal, symptomatic therapy. The dialysis is noneffective.
Way of application and dose
Inside. A recommended initial dose - on 5 mg a day, in need of it it is possible to enlarge 3 times by 5 mg each 2-3 days. An average daily dose - 20-30 mg. The maximum single dose - 30 mg, daily - 60 mg.
Safety measures
With care to apply simultaneously with neuroleptics, antidepressants, warm glycosides, antihypertensive and antidiabetic agents, peroral contraceptives. At renal and hepatic insufficiency easy and moderate severity level, a cirrhosis prescribe in smaller doses and under the strict control of the doctor. In treatment it is necessary to exclude the alcohol use. In the beginning of treatment with care to apply in an operating time to drivers of vehicles and the people which trade is bound to the raised concentration of attention.
Special indicatings
It is necessary to consider, that the alarm or a strain bound to daily stress.
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