Remeron
Remeron (Mirtazapine)Pharmacological action
Antidepressant. Blocks the central presynaptic a2-receptors that raises. Weakens expression of such symptoms as psychomotor block, dream disturbances, depression of mass of a body, suicidal thoughts, mood swings, loss of interest to a life. Antidepressive action develops in 7-14 days of treatment.
Indications
- The depressions demanding pharmacotherapy.
Dosage regimen
For adults the effective daily dose usually makes 15-45 mg. A standard daily dose-30 mg. 1 time/sut before a dream is prescribed mainly.
Therapy than 4-6 months are necessary to continue after full disappearance of clinical symptoms of depression yet less the Preparation it is necessary to cancel gradually.
At elderly patients a recommended dose same, as at patients of younger age.
Clinical researches on application of a preparation for children were not spent.
Side effect
Probably: some intensifying of appetite and augmentation of mass of a body, drowsiness in the first weeks of treatment.
Seldom: an orthostatic hypotension.
Very seldom: cramps, a tremor, a myoclonus, edemas, rising of activity of transaminases of plasma, dermal rashes, reversible oppression of a medullar hemopoiesis.
Contraindications
- A hypersensibility to Remeron (Mirtazapine).
Pregnancy and lactemia
Clinical data about efficiency and safety of Remeron application at pregnancy and in a lactemia are absent.
Special indicatings
With care prescribe a preparation the patient with an epilepsy and organic lesions of a brain, with disturbances of function of a liver and-or kidneys, an acute cardiovascular pathology, with an arterial hypotension, to patients with the acute angle-closure glaucoma, a sick diabetes.
It is necessary to mean, that at occurrence in reception of a preparation of such symptoms as the fervescence, a pharyngalgia, a stomatitis treatment should be stopped and made the clinical analysis of blood.
Remeron is not necessary to prescribe simultaneously with inhibitors MAO and within 2 weeks after their cancellation.
In treatment by a preparation it is necessary to abstain from the alcohol use.
Influence on ability to driving of motor transport and to management of mechanisms
With care prescribe Remeron to the patients who are engaged in potentially dangerous kinds of activity, demanding special attention and speed of psychomotor reactions (including motor transport driving).
Overdosage
Symptoms: block, drowsiness.
Treatment: a gastric lavage, the activated coal, symptomatic therapy.
Conditions and periods of storage
The preparation should be stored in the dry place protected from light at temperature from 2 to 30 C. The Period of validity - 3 years.
Conditions of holiday from drugstores
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