Minocin
Minocin (Minocycline)Pharmacological action
A semisynthetic antibiotic from group of Tetracyclinums. Minocin (Minocycline) interferes with reproduction of bacteria and possesses a wide spectrum of action. It is active concerning Mycoplasma pneumoniae, Haemophilus influenzae, Klebsiella, Streptococcus pneumoniae and other strains Streptococcus, Staphylococcus aurens, Clostridium, Acti - nomyces, Chlamidia, Neisseria meningitidis.
Indications to Minocin (Minocycline) application
The bacteriemic infections caused by microorganisms sensitive to a preparation: infections of the top and bottom respiratory tracts; an ornithosis (the acute infectious disease transferred to the person from birds), a psittacosis (the acute infectious disease transferred to the person from birds), urethrites, Reiter syndrome (the infectious-allergic illness characterised by a combination of an urethritis of a/inflammation of urinary ways/, a conjunctivitis of a/inflammation of an external cover of an eye / and plural damage of joints), conjunctivitises, a trachoma (an infectious disease of eyes which can lead to blindness), a venereal lymphogranulomatosis (an inguinal lymphogranulomatosis / IV venereal illness / - the illness transferred sexual by; it is characterised by an inflammation of inguinal lymph nodes with the subsequent formation of bleeding ulcers); Plague, tularemia (the acute infectious disease transferred to the person from animals), a malignant anthrax, a cholera, an infectious disease transferred to the person, as a rule, from agricultural animals, a garapata disease (a typhoid returnable epidemic - the infectious disease transferred by pincers and characterised by numerous, irregular liftings of a body temperature); infections of a skin and the soft tissues, caused Streptococcus, Staphylococcus aurens. Treatment of asymptomatic carriers Neisseria meningitidis.
Preparation do not apply to treatment of a meningococcal infection and for treatment of any infections caused Staphylococcus aureus. For the patients possessing a hypersensibility to Penicillinums, Minocin (Minocycline) apply as an alternative medical product at following infections: a gonorrhea, listeroses (the infectious disease of animals transferred to the person; it is characterised by numerous lesions of lymph nodes, presence in blood of microbes without formation of the centres of a purulent inflammation in tissues/), actinomycoses (fungoid diseases); the infections caused Clostridium.
Way of application and dose
Before appointment it is desirable for patient of a preparation to define sensitivity to it of the microflora which have caused disease at the given patient. Doses establish individually depending on gravity of a current of an infection and sensitivity of a microorganism to a preparation. The average initial dose of a preparation for adults makes 0,2 g, further - 0,1 g everyone 12 h. To children is more senior 8 years prescribe in an initial dose of mass of a body of 4 mg/kg, further - 2 mg/kg of mass of a body everyone 12h. Therapy should be continued not less than 24-48 h after improvement of a condition sick (disappearances of symptoms and temperature depression). At a syphilis prescribe in an initial dose 0,2 g, further - 0,1 g everyone 12 h within 10-15 days. At a gonorrhea duration of treatment makes not less than 7 days. At a meningococcal carriage (presence in an organism of the originator of a meningitis without implication of symptoms of disease) a preparation prescribe in a dose 0,1 g everyone 12 h within 5 days. The preparation should be accepted for 1 h to meal or through 2 h after meal. With the expressed disturbances of function of kidneys and-or a liver it is necessary for patients to prescribe a preparation in a smaller dose.
Minocin (Minocycline) Side effect
The anorexia (absence of appetite), a nausea, vomiting, diarrhoeia, a dysphagia (dysphagia), rising of activity of hepatic enzymes in blood are possible; an erythematic eruption (kinds of a dermal eruption), a skin hypersensibility to a sunlight, shown in excessive sunburn; hypersensibility reactions - an urticaria, arthralgias (an articulate pain),-development of an anaphylactic (allergic) shock is rare. Occurrence of a headache and giddiness which can independently disappear at treatment continuation, and also right after its terminations is possible. At occurrence of first signs of a dermal erythema treatment by a preparation should be stopped.
Contraindications
A hypersensibility to Tetracyclinums, pregnancy. Do not prescribe to children till 8 years. The preparation should be prescribed with care the patient with the indicating to allergic reactions in the anamnesis (case history).
The release form
The tablets containing on 0,05 and 0,1 g Minocin (Minocycline) of hydrochloride, in packing on 100 and 50 pieces, accordingly. The capsules containing on 0,05 and 0,1 g Minocin (Minocycline) of hydrochloride, in packing on 100 and 50 pieces. Suspension (suspension) for peroral (through a mouth) applications (5 ml - 0,05 g of Minocin (Minocycline) a hydrochloride) in vials.
Storage conditions
The list. In the dry, cool place protected from light.
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