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Dramamine

Dramamine (Dimenhydrinate)

Pharmacological action

A blocker of histaminic H1-receptors. Renders sedative, antiemetic action.
Oppresses vestibular stimulation, operating first of all on otoliths; in high doses an effect has on semicircular channels.

Indications

- Minyear Illness;
- Vestibular disturbances.

Dosage regimen

The adult prescribe a preparation on 50-100 mg 2-3 times/days the Maximum daily dose should not exceed 300-400 mg.
To children at the age from 1 year till 6 years the preparation is prescribed on 12 mg by 3 times/sut, from 7 till 12 years - on 25-50 mg 3 times/days
Preparation accept to meal.
For preventive maintenance it is necessary to accept 50-100 mg for 30 mines to a trip.

Side effect

From party TSNS: giddiness, a headache, drowsiness, retardation of impellent reactions, the general delicacy, accommodation disturbance.
From the alimentary system: dryness in a mouth, a nausea.

Contraindications

- Children's age till 1 year;
- Pregnancy;
- A lactemia (thoracal feeding);
- A hypersensibility to preparation components.

Pregnancy and lactemia

Dramamine preparation is contraindicative to application at pregnancy.
In need of Dramamine application in a lactemia it is necessary to stop thoracal feeding.

Special indicatings

With care Dramamine prescribe to patients with a convulsive syndrome, at an angle-closure glaucoma, a good-quality hyperplasia of a prostate, to patients with a bronchial asthma.
Influence on ability to driving of motor transport and to management of mechanisms
With care it is necessary to prescribe a preparation to the patients who are engaged in potentially dangerous kinds of activity (including motor transport driving), demanding special attention and speed of psychomotor reactions.

Overdosage

Symptoms: dryness in a mouth, in a nose and a throat, the face reddening which has been slowed down and complicated breath, confusion of consciousness.
Treatment: a gastric lavage, reception of the activated coal, symptomatic therapy.

Medicinal interaction

At simultaneous Dramamine application to sedative, somnolent preparations, antidepressants, ethanol there is an intensifying of their oppressing action.

Conditions and periods of storage

The preparation should be stored in a dry place.

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