Imodium
Imodium
Imodium (Loperamide)Pharmacological action
Anti Diarrhoeia preparation. Suppresses liberation of Acetylcholinum and Prostaglandinums, reducing thereby a peristalsis and enlarging time of passage of contents on an intestine. Raises a tonus of a proctal sphincter, reducing an incontience of fecal masses and desires on a defecation.
Indications
- An acute and chronic diarrhoeia;
- For the purpose of regulation of a chair at patients.
Dosage regimen
Preparation prescribe inside.
At an acute diarrhoeia to adults and patients of advanced age prescribe in an initial dose of 4 mg, further - on 2 mg after each certificate of a defecation in case of a liquid chair. To children is more senior 6 years prescribe in an initial dose of 2 mg, further - on 2 mg after each certificate of a defecation in case of a liquid chair.
At a chronic diarrhoeia to adults and patients of advanced age prescribe in an initial dose - 4 mg/days correct Further a dose so that frequency of a chair made 1-2 times a day, that is usually reached at a maintenance dose from 2 to 12 mg in days to Children is more senior 6 years prescribe in an initial dose of 2 mg. Further a dose correct so that frequency of a chair made 1-2 times a day, that is usually reached at a maintenance dose from 2 to 12 mg in days
The maximum daily dose at an acute and chronic diarrhoeia at adults - 16 mg; at children - 6 mg on 20 kg of mass of a body - to 16 mg.
At occurrence of a normal chair or in the absence of a chair more than 12 h a preparation cancel.
Side effect
From the alimentary system: a constipation and-or an abdominal distention, an intestinal colic, a pain or discomfort in a stomach, a nausea, vomiting, dryness in a mouth; on occasion - intestinal impassability.
From party TSNS and peripheric nervous system: fatigability, drowsiness, giddiness.
From a metabolism: a hypovolemia, reduction of the maintenance of electrolytes.
Allergic reactions: a dermal eruption.
The other: the feeling of a burning sensation or the tongue pricking, arising right after reception of a preparation in the form of tablets for a resorption is possible; seldom - an ischuria.
Contraindications
- An acute dysentery and other infections GASTROINTESTINAL TRACT (caused, including Salmonella spp., Shigella spp., Campylobacter spp.);
- Intestinal impassability (including if necessary to avoid peristalsis suppression);
- A divertuculosis;
- An acute ulcerative colitis;
- A pseudomembranous coloenteritis (a diarrhoeia caused by reception of antibiotics);
- I trimester of pregnancy;
- The lactemia period;
- Children's age till 6 years;
- A hypersensibility to Imodium (Loperamide) and-or to other components of a preparation.
Pregnancy and lactemia
Imodium is contraindicative in I trimester of pregnancy.
Imodium in small amounts it is allocated with thoracal milk, therefore in need of application of a preparation in a lactemia thoracal feeding should be stopped.
Special indicatings
With care it is necessary to prescribe a preparation at hepatic insufficiency.
Preparation reception is necessary for stopping immediately if the constipation or an abdominal distention develops.
As treatment of diarrhoeia Imodium has only symptomatic character, along with it it is necessary to apply etiotropic agents, whenever possible.
At a diarrhoeia, especially children, can have hypovolemia and depression of the maintenance of electrolytes. In such cases of the most important replaceable therapy for a restore of a liquid and electrolytes is. At an acute diarrhoeia if during 48 h it is not observed clinical improvement, reception Imodium is necessary to stop and exclude an infectious genesis of a diarrhoeia.
Not to apply at a diarrhoeia with a blood impurity in a chair and a heat.
At patients AIDS it is necessary to stop immediately treatment at abdominal distention first signs. On occasion at patients AIDS with infectious colitises both virus, and the bacteriemic nature at Imodium treatment can develop a toxic megacolon.
Patients with disturbance of function of a liver should be under careful observation for the purpose of timely revealing of signs of toxic lesion Central Nervice system.
In treatment observance of a diet and a liquid restore is recommended.
It is necessary to mean, that tablets for a resorption fragile enough, therefore in order to avoid damage they cannot be pressed through through a foil.
Influence on ability to driving of motor transport and to management of mechanisms
In treatment it is necessary to refrain from driving of transport and employment by potentially dangerous kinds of the activity demanding raised concentration of attention and high rate of psychomotor reactions.
Medicinal interaction
Medicinal interaction of Imodium preparation it was not observed.
Conditions and periods of storage
The preparation should be stored in a place inaccessible to children at temperature from 15 to 30 C. The Period of validity - 5 years.
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