Mysoline
Mysoline
Mysoline (Primidone)Anticonvulsant preparation
Structure
1 tablet contains 0,25 h Primidonum
Pharmacological action
Antiepileptic preparation. Anticonvulsant an effect has and causes weakly expressed somnolent effect.
Pharmacokinetics
At Mysoline intake quickly and almost it is completely absorbed from GASTROINTESTINAL TRACT. Bioavailability makes 90-100 %. The maximum concentration of Primidonum in a blood plasma is observed through 3 h.
The semideducing period makes 7-14 h. The preparation is metabolized with phenobarbital formation (about 20 %).
Indications to application
The epilepsy of a various genesis.
Is less effective at focal, myoclonic, akinetic attacks.
Dosage regimen
Mysoline accept inside after meal. An initial daily dose for adults of 125 mg (in 1-2 receptions), then enlarge a dose each 3 days by 125 mg before achievement of necessary effect.
The maximum doses for adults: single - 750 mg, daily - 2
To children depending on age prescribe from 125 mg to 500 mg a day.
The maximum daily dose for children - 1 h (in 2 receptions).
Side effect
Are possible: easy drowsiness, apathy, giddiness, a headache, psychotic reactions, a nystagmus ; a nausea, vomiting.
Are noted: a leukopenia, a lymphocytosis; seldom -a "lupoid" syndrome, arthralgias.
Contraindications
Diseases of a liver and-or kidneys;
Diseases of system of a hemopoiesis;
Pregnancy;
Lactemia;
Hypersensibility to Primidonum.
Special indicatings
Mysoline can be used in complex anticonvulsant therapy. Cancellation of a preparation and its replacement spend gradually. It is necessary to be careful at Mysoline appointment to children, the elderly and weakened patients. At long application development of medicinal dependence is possible.
With care prescribe Mysoline to the patients who are engaged in potentially dangerous kinds of activity, demanding special attention and speed of impellent and mental reactions.
It is not necessary to prescribe a preparation in I trimester of pregnancy.
In need of appointment of a preparation in a lactemia it is necessary to solve a question on the termination of thoracal feeding.
Medicinal interaction
At simultaneous Mysoline appointment and paracetamol action of the last can be weakened. Mysoline also reduces clinical efficiency of Chinidinum. Oppression Central nervice system and respirations can amplify at simultaneous Mysoline application.
Buy Mysoline online
Here you can order Mysoline online. Cheap Mysoline, just click the link below.
$1.32
