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Low doses of estrogens can help at relapses of a cancer of a mammary gland
At relapses of a cancer of a mammary gland, arisen after course of treatment and despite it, very low doses of estrogens can help.Some tumours of a mammary gland "feed" the estrogens, therefore many methods of treatment cancer of a mammary gland are referred on suppression of production of this hormone, however after some years of such therapy to an organism small doses of estrogens can be demanded to cope with cancer relapse.
The results of research published in "Magazine of the American medical association", can become a basis for working out of a cheap and effective way to help patients with late stage cancer of a mammary gland.
Dr. Matthew Ellis and its colleagues from Medical school at University of George Vashingtona in Saint Louis (Missouri, the USA) surveyed 66 women with late stage cancer of a mammary gland which received treatment by modern preparations - aromatase inhibitors.
"All participants of research had relapses cancer of a mammary gland, despite reception of the preparations suppressing production of estrogens, and their disease progressed, - Dr. Ellis explains. - to Them does not remain anything, except chemotherapy, but low doses of estrogens have allowed to stop advance of illness at many of them and they were transferred by patients where better, than chemotherapy".
Researchers gave to women estrogens in the form of Oestradiolum - the part from them received a high dose of a preparation, a part - low. Irrespective of a positive effect dose it was possible to achieve from 30 % of participants.
"The data obtained by us have clearly shown, that estrogens help with low doses at metastasizing cancer of a mammary gland not worse, than high, and thus are better transferred by patients", - speaks Matthew Ellis.
The effect of low doses of estrogens not always was to constants. After time at 30 % of all women to which were helped by estrogens, tumours have started to grow again. But at third from them advance has stopped against repeatedly prescribed inhibitors of an aromatase - on 1 capsule a day - which are much less toxic, than the preparations applied at chemotherapy.
Every year all over the world from cancer of a mammary gland 400 000 women perish. About 75 % of malignant tumours of a mammary gland contain receptors of estrogens, and it means, that estrogens will be "feed" such tumour. In these cases the patient prescribe such preparations, as Tamoxifenum and the inhibitors of an aromatase suppressing production of estrogens.









