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Essentially new antibiotic will disorient dangerous bacteria
Scientists from the Southwest medical centre at University of Texas have found out, that bacteria E. coli, Salmonella, and Francisella tularensis (the tularemia originator) distinguish a human body by means of the special receptor reacting to such hormones as adrenaline and Noradrenalinum. Virulent genes of bacteria are thus activated and infectious process is started microbic toxins, in particular, start to be formed. The antibiotic under name LED209 blocks this receptor, not killing a bacterium, but doing their harmless to the person.The principal of Vanessa Sperandio research and its colleagues have tested LED209 antibiotic on the mice infected with a salmonellosis, a tularemia or the intestinal infection caused E. сoli. Treatment has appeared effective. It was found out, that the animals receiving a medicine to, or in some hours after infection, felt better and survived much more often those who took placebo. Thus serious by-effects it has not been registered.
Scientists have noticed, that the spectrum of action of a new preparation is not limited to three tested bacteria. The receptor on which the antibiotic operates, is available at least for 25 pathogenic microorganisms - in particular, exciter legionellosis. Special advantage of a new preparation is that it, possibly, will not cause development of medicinal fastness as does not destroy pathogenic bacteria, experts consider









