Medrol
Medrol
Medrol (Methylprednisolone)Pharmacological action
Synthetic glucocorticoid preparation. Antiinflammatory, immunodepressive and antiallergic an effect has; influences a carbohydrate, albuminous, lipide exchange.
Reduces quantity of immunocompetent cells in the locus of an inflammation, lowers development of Prostaglandinums.
Methylprednisolone has more expressed antiinflammatory an effect and less expressed action, than a hydrocortisone.
Medrol Indications
- Collagenoses (including a system lupus erythematosus, a pseudorheumatism, a seronegative spondylarthritis);
- Allergic responses, an acute anaphylaxis;
- A bronchial asthma of serious flow;
- An ulcerative colitis;
- A glomerulonephritis;
- A virus hepatitis;
- An eczema and a neurodermite demanding treatment by glucocorticoids;
- A leukaemia, a myeloma, a lung cancer (in a combination with cytostatics);
- Cupping of a nausea and the vomiting, arising against cytostatic therapy.
Dosing regimen
Establish individual according to disease severity level.
Inside the adult prescribe in a maintenance dose of 4-12 mg/days the Initial dose often happens considerably above (16-96 mg/sut). In need of long treatment a maintenance therapy spend a preparation in the minimum effective dose.
Preparation recommend to accept in the morning in day.
I.v. in prescribe a preparation in a dose of 100-500 mg. At a shock and at reaction of a graft rejection of a dose it is possible to enlarge about 30 mg/kg during the short season. At i.v. injections of a preparation in high doses duration of injection should compound not less than 10 minutes
For cupping of a nausea and the vomiting, the cytostatic preparations invoked by reception, Medrol is prescribed in a dose by of 250 mg for 20 mines before reception. If necessary Medrol in this dose can be prescribed repeatedly everyone 6 h.
For children Medrol dose should be reduced, but thus it should compound not less than 25 mg/days
Rules of preparation of injection solutions
For preparation of solution for i.v. injections it is necessary to add 4 ml of a dissolvent from the applied ampula to vial contents. The received solution has concentration of 62.5 mg/ml.
For preparation of solution for i.v. injection to the prepared solution it is necessary to add 100-1000 ml of solution of 5 % Dextrosums, a normal saline solution or their admixture.
Medrol Side effect
From endocrine system: an Icenco-Cushing syndrome, an atrophy of a cortex of adrenals.
From a metabolism: carbohydrate metabolism disturbances, augmentation of mass of a body, an osteoporosis.
From the alimentary system: development of stomach ulcers and an intestine is possible.
From party TSNS: alienations, ophthalmotonus rising.
From cardiovascular system: development of an arterial hypertensia is possible.
From the immune status: depression of fastness to infectious diseases.
Medrol Contraindications
- A tuberculosis;
- Acute both chronic bacteriemic and virus infection contaminations (without due chemotherapeutic protection).
The special indicatings
It is necessary to be careful at simultaneous application of Medrol with peroral hypoglycemic preparations, anticoagulants, Salicylases, barbiturates and diuretics.
Use in pediatrics
At carrying out of an injection of Methylprednisolone it is necessary for newborn and, especially, not full-term child to use the distilled water as a dissolvent.
Overdosage
Now about cases of an overdosage of a preparation Medrol did not intercommunicate.
Medrol Medicinal interaction
At simultaneous application Medrol can reduce action of Salicylases.
At joint application Medrol action can decrease under the influence of Phenytoinum, barbiturates.
Conditions and periods of storage
Period of validity - 5 years.
Buy Medrol online
Here you can order Medrol online. Cheap Medrol, just click the link below
$1.01
