Mestinon
Mestinon
Mestinon (Pyridostigmine)Pharmacological action
Acetylcholinesterase inhibitor. Indirect cholinomimetic an effect at the expense of reversible inhibition of an acetylcholinesterase and intensifying of action of endogenous Acetylcholinum has. Enriches a neuromuscular transmission, enhances a motility GASTROINTESTINAL TRACT, raises a tonus of a bladder, bronchuses, secretion of excretory glands, invokes a bradycardia, a weak miosis, an accommodation spastic stricture.
Mestinon Indications
- A myasthenia;
- A myasthenic syndrome;
- A musculation atony GASTROINTESTINAL TRACT;
- A bladder atony.
Mestinon Dosing regimen
At at initial symptoms of a myasthenia the preparation is prescribed in a daily dose by of 30-120 mg in 1 or 2 receptions, at disease advance - 120-720 mg in 2-4 receptions. The maximum daily dose - 720 mg.
At an atony of a musculation of a gastrointestinal tract and a bladder Mestinon is prescribed in a dose on 60 mg by everyone 4 h.
Side effect
From the alimentary system: a nausea, vomiting, a diarrhoeia, abdominal pains, peristalsis intensifying.
From cardiovascular system: a bradycardia and BP depression.
Dermatological reactions: a dermal eruption (it is caused by the maintenance in bromine preparation).
The other: a hypersecretion of bronchial Ferri lactases, a hypersalivation, a dacryagogue, a sweating, a frequent emiction, a miosis, cramps, muscular delicacy.
Mestinon Contraindications
- Hypersensitivity to preparation components;
- intestinal impassability;
- A spastic stricture of cholic and urinary pathes;
- Spastic states of members GASTROINTESTINAL TRACT;
- A shock in the postoperative season;
- A thyrotoxicosis;
- A parkinsonism;
- A bronchial asthma;
- A chronic obstructive bronchitis;
- An iritis;
- A lactemia (thoracal feeding).
Considering the high maintenance of reacting material, Mestinon do not apply to treatment of an atony of a musculation GASTROINTESTINAL TRACT and a bladder at children is more younger 16 years.
With guard it is necessary to prescribe a preparation at an arterial hypotension, warm and renal insufficiency, an acute myocardial infarction, a peptic ulcer of a stomach and a duodenum, a bradycardia, a diabetes, operations on GASTROINTESTINAL TRACT, liver diseases.
Pregnancy and lactemia
With guard it is necessary to prescribe a preparation at pregnancy.
Mestinon is contraindicative in a lactemia (thoracal feeding).
Mestinon The special indicatings
The patient with diseases of nephroses a preparation prescribe in lower doses. A necessary dose select individual.
The patient should be informed that if he has forgotten to accept in due time the next dose of a preparation, it is not necessary to accept this dose in addition to the ordered scheme of dosing.
In the course of treatment by the patient the alcohol use is forbidden.
Influence on ability to driving of motor transport and to control of mechanisms
Mestinon can invoke retardation of rate of psychomotor reactions. It is necessary to avoid driving of the car and employment by other kinds of the activity demanding high concentration of attention, speed of psychomotor reactions.
Mestinon Overdosage
Symptoms: augmentation of secretion of the lacrimal, salivary and sudoriferous Ferri lactases, a dermahemia, sharp delicacy, sight disturbance, a miosis, giddiness, a nausea, vomiting, a consensual defecation and an emiction, an intestinal colic, a bronchospasm, a fluid lungs, the expressed or accruing muscular delicacy, a paralysis of respiratory muscles, BP depression, a collapse, a bradycardia, a paradoxical tachycardia, a cardiac standstill.
Treatment: preparation cancellation, i.v. introduction (slowly) Atropini sulfas in a dose of 1-2 mg. If necessary and depending on the CARDIAC CONTRACTIONS RATE probably repeated introduction of Atropini sulfas in the same dose through 2-4 h. Spend symptomatic therapy.
Mestinon Conditions and periods of storage
A.Preparat's list should be stored at temperature not above 30 C. The Period of validity - 3 years.
Buy Mestinon online
Here you can order Mestinon online. Cheap Mestinon, just click the link below.
$2.12
